NVHG & BeSHG

SYMPOSIUM 2019

19 & 20 september,  Koninghof, Veldhoven (NL)



Flyer NVHG 2019.jpg


Our sponsors:

Logo Stichting Simonsfonds_RGB.jpg     

logo_Agilent-2018.png     logo_SophiaGenetics-2018.jpg      logo_PerkinElmer-2019.jpg

      logo_illumina-2018.jpg     logo_diploid_2019.png     logo_Takara_BrandTri-2019.png





logo_SanofiGenzyme-2018.jpg   logo_PacBio-2018.jpg   logo_Macrogen-2018.jpg   logo_Sanbio-2019.png    



logo_BGI-2018.PNG   logo_Westburg-2019.jpg   logo_NimaGen-2018.jpg   logo_Hettich-2019_.jpg  


logo_Bioke-2019logo.jpg    Logo_Twist-2019.jpg   logo_Thermo Fisher Scientific - 2019.jpg  logo_GE Heathcare_2019.png    



  logo_Novogene-2018.png     logo_Bionano_CMYK_2019.jpg     logo_Alnylam_2019.png




Venue

  NH KONINGSHOF.png

Hotel NH Eindhoven Conference Centre Koningshof

Locht 117, 5504 RM Veldhoven

Eindhoven - Nederland

Tel.: +31 40 253 7475

www.nh-hotels.nl/hotel/nh-eindhoven-conference-centre-koningshof

nhkoningshof@nh-hotels.com



Final Program

(Last update 17-09-2019)


Time

 


Thursday  19th  September


09:30 - 10:30


Registration

 

Room: Holland Foyer

 

 

 

10:30 - 12:40

Opening & Plenary session 1

 

 

Room: Auditorium

 

 

Chair: Mieke van Haelst (NVHG) / Saskia Bulk (BeSHG)

 

 

 

10:30

 

Opening by Dr. Mieke van Haelst president NVHG / Dr. Saskia Bulk board member BeSHG


10:35

 


Prof. Dr. John van der Oost (Wageningen, NL)

 

 

CRISPR-Cas – from biology to applications


11:15

 


DNA Day Contest Award


11:20

 


Prof. Dr. Douglas Easton (Cambridge, UK)

 

 

Predicting Breast Cancer Risk using Rare and Common Variants


12:00

 


Lodewijk Sandkuijl Lecture: Danielle Posthuma (Amsterdam, NL)

 

 

  From GWAS to Function

 

 

 

 

 

 

12:40 - 14:00

Lunch, room: Holland Foyer


13:00

 


Business/private meetings VKGN

 

 

Room: Parkzaal


13:00

 


Business/private meetings VKGL

 

 

Room: Auditorium

 

 

 

 

 

 

14:00 - 16:00

Plenary session 2

 

 

Room: Auditorium

Chair: Terry Vrijenhoek (NVHG) / Bert Callewaert (BeSHG)

 

 

Hurdles for genetic research - what can we do about them?

Panel session to explore how genetic research could be further facilitated

14:00

 

Introduction session

14:15

 

Panel presentation and hurdle identification

15:00

 

Power Break

15:15

 

Plenary discussion - how to overcome the hurdles

15:45

 

Conclusion in images

 

 

 

 

 

 

 

 

 

16:00 - 17:30

Posters presentation with coffee & tea           Room: 65 / Holland Foyer

 

 

 

 

 

 

17:30 - 18:30 

Plenary session 3

 

 

Room: Auditorium

Chair: Johan den Dunnen (NVHG)


17:30

 


Prof. Dr. Peter de Knijff  (Leiden, NL)

 

 

A result is only a result if it results in a result

 

 

 

 

 

 

18:30 - 21:00

Social Evening Program

 

 

Room: Brabantzaal


18:30

 


Pre-dinner drinks

19:00

 

Dinner

21:00

 

Networking event

 

 

 


Time

 


Friday  20th  September


08:30 - 09:30


Registration

 

 

Room: Holland Foyer

 

 

 

08:45 - 10:05 

Plenary session 4

 

 

Room: Auditorium

 

 

Chair: André Uitterlinden (NVHG) / Saskia Bulk (BeSHG)


8:45

 


Prof. Dr. Michel Georges (Liege, BE)

 

 

Identifying causative variants and genes in GWAS-identified IBD risk loci

9:25

 

Prof. Dr. Elfride De Baere (Ghent, BE)

 

 

Integrated omics to accelerate diagnosis and therapy in inherited retinal diseases causing blindness

 

 

 

10:05 - 11:15 

Parallel sessions A/B

 

 

 

 

 

A. Fertility and Pregnancy

 

 

Room: Auditorium

 

 

Chair: Lidewij Henneman (NVHG)  / Björn Menten (BeSHG)


10:15

 


Martine De Rycke

 

 

Preimplantation Genetic Testing with HLA matching: from counselling to birth and beyond

10:30

 

Karuna van der Meij

 

 

TRIDENT-2: National Implementation of Genome-Wide Non-Invasive Prenatal Testing as a First-Tier Screening Test in the Netherlands

10:45

 

Kris Van Den Bogaert

 

 

The landscape of pathogenic copy number variations in healthy, reproducing females

11:00

 

Masoud Zamani Esteki

 

 

In vitro fertilization does not increase the incidence of de novo copy number alterations in fetal and placental lineages

 

 

B. Personalized Genomics

 

 

Room: Parkzaal

 

 

Chair: Gijs Santen (NVHG) /  Damien Lederer (BeSHG)


10:15

 


Inge Lakeman

 

 

Longitudinal assessment of the 313-SNP based Polygenic Risk Score for breast cancer risk prediction in a Dutch prospective cohort

10:30

 

Helen Roessler

 

 

Towards the treatment of Cantú syndrome

10:45

 

Remco Hack

 

 

NOTCH3 cysteine altering variants and their phenotypes in 92,456 whole exome sequenced participants of the Geisinger DiscovEHR initiative

11:00

 

Eline van Hugte

 

 

Towards personalized treatment of genetically classified refractory epilepsies using human induced pluripotent stem Cells (hIPSCs) as an ex-vivo tool

 

 

 


11:15 - 11:45 


Poster viewing with coffee & tea              Room 65 / Holland Foyer

 

 

 

11:45 - 12:45

Parallel sessions C/D

 

 

 

 

 

C. Diagnostic Opportunities

 

 

Room: Auditorium

 

 

Chair: Richard Sinke (NVHG) /  Kris Van Den Bogaert (BeSHG)


11:45

 


Jeroen van Rooij

 

 

Genotyping On ALL patients (GOALL); clinical implementation of high-throughput genotyping arrays.

12:00

 

Kornelia Neveling

 

 

The added value of long-read amplicon sequencing for clinical applications

12:15

 

Peter Henneman

 

 

Reliable application of DNA-methylation signatures in genetic diagnostic testing

12:30

 

Helga Westers

 

 

What if we would use a diagnostic multi-cancer gene panel for opportunistic screening? A study in 2,090 Dutch familial cancer patients

 

 

 

 

 

D. Biological Insight into Rare Disease

 

 

Room: Parkzaal

 

 

Chair: Lisenka Vissers  (NVHG) /  Arvid Suls (BeSHG)


11:45

 


Margot Reijnders

 

 

Neurodevelopmental disorders: a next generation

12:00

 

Lore Pottie

 

 

Transcriptome and protein analysis highlight the endosomal pathway in disease pathogenesis of metabolic CL syndrome

12:15

 

Eva D'haene

 

 

Noncoding structural variants disrupt the regulatory architecture of Rett genes

12:30

 

Daphne Smits

 

 

Loss of neutral sphingomyelinase-3  (SMPD4) links neurodevelopmental disorders to cell cycle and nuclear envelope anomalies

 

 

 

 

 

 

12:45 - 14:00

 

Lunch and poster viewing

13:00

 

NVHG General Members' Meeting

Room: Auditorium

 

 

 

 

 

 

14:00 - 16:30

Plenary session 5

 

 

Room: Auditorium

 

 

Chair: Roland Kuiper (NVHG)  / Bert Callewaert (BeSHG)


14:15

 


Prof. Dr. Joris Veltman (Newcastle, UK)

 

 

De novo mutations affecting male reproductive health

14:55

 

PD. Dr. Malte Spielmann (Berlin, DE)

 

 

Human genetics at single cell resolution

15:35

 

Winner Genetics Retreat 2019 : Lisanne Vervoort ( Leuven, BE)

 

 

Optical Mapping of 22q11.2 Low Copy Repeats reveals structural hypervariability

 

 

 


16:00

 


Awards 2019

 

 

Chair: Mieke van Haelst (NVHG) / Bert Callewaert (BeSHG)

 

 

Young Investigator Award (for best thesis)
Annual Award (for best oral presentation)
Poster Award (for best poster)
Puzzle prize

16:15

 

Closing Remarks

16:30

 

Meeting ends

 

 

 



At the meeting a short printed program will be available. All other material (program book, abstracts) will be available in electronic format only.



History